Are you looking for a comforting, hearty meal that the whole family will love? Did you know that casseroles are one of the most popular family-friendly dishes for their versatility and ease of preparation? This Homemade Cheesy Beef & Vegetable Casserole is a must-try recipe that combines savory ground beef, fresh vegetables, and gooey cheese for a satisfying dinner. Let’s dive into the details of making this delicious dish!
Ingredients List
To prepare this Cheesy Beef & Vegetable Casserole, you will need the following ingredients:
- For the Casserole:
- 1 pound ground beef
- 1 medium onion (diced)
- 2 cloves garlic (minced)
- 2 cups mixed vegetables (frozen or fresh, such as carrots, peas, and corn)
- 1 can (15 ounces) diced tomatoes (drained)
- 1 cup cooked rice (white or brown)
- 1 teaspoon Italian seasoning
- Salt and pepper to taste
- For the Cheese Sauce:
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 1 cup milk
- 1 ½ cups shredded cheddar cheese
- ½ cup grated Parmesan cheese
Substitution Suggestions:
- Ground Turkey:Â Substitute ground beef with ground turkey or chicken for a leaner option.
- Vegetarian Version:Â Use lentils or chickpeas instead of meat and add more vegetables for a vegetarian casserole.
Step-by-Step Instructions
Step 1: Preheat the Oven
Preheat your oven to 350°F (175°C). This ensures that your casserole cooks evenly and thoroughly.
Step 2: Cook the Beef
- Brown the Beef:
- In a large skillet over medium heat, add the ground beef and diced onion. Cook until the beef is browned and the onion is soft, about 5-7 minutes. Drain any excess fat.
- Add Garlic:
- Stir in the minced garlic and cook for another 1 minute until fragrant.
Step 3: Combine Ingredients
- Add Vegetables and Rice:
- To the skillet, add the mixed vegetables, drained diced tomatoes, cooked rice, Italian seasoning, salt, and pepper. Mix well and remove from heat.
Step 4: Make the Cheese Sauce
- Melt Butter:
- In a saucepan over medium heat, melt the butter.
- Add Flour:
- Whisk in the flour and cook for about 1 minute to form a roux.
- Add Milk:
- Gradually whisk in the milk, stirring constantly until the mixture thickens, about 3-5 minutes.
- Add Cheese:
- Remove from heat and stir in the cheddar and Parmesan cheeses until melted and smooth.
Step 5: Assemble the Casserole
- Combine Mixtures:
- Pour the cheese sauce over the beef and vegetable mixture, stirring until everything is well coated.
- Transfer to Baking Dish:
- Pour the entire mixture into a greased 9×13-inch baking dish, spreading it evenly.
Step 6: Bake the Casserole
- Bake:
- Place the casserole in the preheated oven and bake for 30 minutes or until bubbly and golden on top.
- Cool Slightly:
- Remove from the oven and let it cool for a few minutes before serving.

Nutritional Information
Here’s a breakdown of the nutritional information per serving (1 cup):
- Calories:Â 400
- Total Fat:Â 20g
- Saturated Fat:Â 10g
- Cholesterol:Â 70mg
- Sodium:Â 600mg
- Total Carbohydrates:Â 30g
- Dietary Fiber:Â 4g
- Sugars:Â 3g
- Protein:Â 25g
This casserole is a balanced meal, providing a good mix of protein, carbohydrates, and vegetables.
Healthier Alternatives for the Recipe
To make this Homemade Cheesy Beef & Vegetable Casserole even healthier, consider these modifications:
- Low-Fat Cheese:Â Use low-fat cheese options to reduce calories and fat content.
- Whole Grain Rice:Â Substitute white rice with brown rice or quinoa for added fiber and nutrients.
- Increase Vegetables:Â Add more vegetables like spinach, bell peppers, or broccoli to boost the nutritional value.
Serving Suggestions
Here are some creative serving suggestions to enhance your Cheesy Beef & Vegetable Casserole:
- Garnish:Â Top with fresh parsley or chives for a pop of color and flavor.
- Side Salad:Â Serve with a side salad dressed with vinaigrette for added freshness.
- Crusty Bread:Â Pair with crusty bread or garlic bread for a complete meal.
Common Mistakes to Avoid
When preparing your Homemade Cheesy Beef & Vegetable Casserole, keep these common pitfalls in mind:
- Overcooking the Beef:Â Avoid overcooking the beef, as it can become dry. Cook just until browned.
- Not Mixing Well:Â Ensure the cheese sauce is fully mixed with the beef and vegetables for even flavor distribution.
- Skipping the Resting Time:Â Letting the casserole sit for a few minutes after baking helps set the layers and makes serving easier.
Storing Tips for the Recipe
To keep your leftovers fresh:
- Refrigeration: Store any leftovers in an airtight container in the refrigerator for up to 3 days.
- Freezing: For longer storage, freeze the casserole in a freezer-safe container for up to 3 months. Reheat in the oven or microwave when ready to eat.
Conclusion
In summary, this Homemade Cheesy Beef & Vegetable Casserole is a comforting and delicious dish that’s perfect for family dinners. With its cheesy goodness and wholesome ingredients, it’s sure to become a staple in your meal rotation. Try this recipe today and share your thoughts in the comments below! Enjoy your cheesy, hearty meal!
FAQs
Can I use different types of cheese?
Absolutely! Feel free to experiment with different cheeses like mozzarella, Monterey Jack, or even feta for unique flavors.
How do I know when the casserole is done?
The casserole is done when it is bubbly and golden on top. You can also check that the internal temperature reaches 165°F (75°C).
Can I make this casserole ahead of time?
Yes! You can prepare the casserole ahead of time and refrigerate it before baking. Just add an extra 10-15 minutes to the baking time if baking straight from the fridge.

Must Try Homemade Cheesy Beef & Vegetable Casserole
Ingredients
- For the Casserole:
- 1 pound ground beef
- 1 medium onion (diced)
- 2 cloves garlic (minced)
- 2 cups mixed vegetables (frozen or fresh, such as carrots, peas, and corn)
- 1 can (15 ounces) diced tomatoes (drained)
- 1 cup cooked rice (white or brown)
- 1 teaspoon Italian seasoning
- Salt and pepper to taste
- For the Cheese Sauce:
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 1 cup milk
- 1 ½ cups shredded cheddar cheese
- ½ cup grated Parmesan cheese
Instructions
Step 1: Preheat the Oven
Preheat your oven to 350°F (175°C). This ensures that your casserole cooks evenly and thoroughly.
Step 2: Cook the Beef
Brown the Beef:
In a large skillet over medium heat, add the ground beef and diced onion. Cook until the beef is browned and the onion is soft, about 5-7 minutes. Drain any excess fat.
Add Garlic:
Stir in the minced garlic and cook for another 1 minute until fragrant.
Step 3: Combine Ingredients
Add Vegetables and Rice:
To the skillet, add the mixed vegetables, drained diced tomatoes, cooked rice, Italian seasoning, salt, and pepper. Mix well and remove from heat.
Step 4: Make the Cheese Sauce
Melt Butter:
In a saucepan over medium heat, melt the butter.
Add Flour:
Whisk in the flour and cook for about 1 minute to form a roux.
Add Milk:
Gradually whisk in the milk, stirring constantly until the mixture thickens, about 3-5 minutes.
Add Cheese:
Remove from heat and stir in the cheddar and Parmesan cheeses until melted and smooth.
Step 5: Assemble the Casserole
Combine Mixtures:
Pour the cheese sauce over the beef and vegetable mixture, stirring until everything is well coated.
Transfer to Baking Dish:
Pour the entire mixture into a greased 9x13-inch baking dish, spreading it evenly.
Step 6: Bake the Casserole
Bake:
Place the casserole in the preheated oven and bake for 30 minutes or until bubbly and golden on top.
Cool Slightly:
Remove from the oven and let it cool for a few minutes before serving.
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